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Product Description

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The product works in the body, much the same way as Viagra and Cialis, it is considered appropriate antibiogico older men who suffer from erectile dysfunction problem. Generic Levitra from Canadian Pharmacy.

Detailed information

Sildenafil is cleared predominantly by the CYP3A4 (major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes. The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized. This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50 of the parent drug. Plasma concentrations of this metabolite are approximately 40 of those seen for sildenafil, so that the metabolite accounts for about 20 of sildenafil's pharmacologic effects.

Note that generic sildenafil comes in several different dosage strengths. For erectile dysfunction, prescriptions usually come in 25 mg, 50 mg, or 100 mg doses (the 20 mg dose is typically used for pulmonary hypertension). Check with your doctor to be sure which one is right for you. Pfizer announced plans to release its own generic version days before Teva8217;s version arrives on the shelves (Teva has planned a generic version since 2013). This will allow Pfizer 8211; which sold more than 1 billion of Viagra in the US in 2016 8211; to keep some of that cashflow coming in. Other generic versions are expected to arrive in pharmacies in the summer of 2018, which should drive prices even lower.

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