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BMJ British Medical Journal 319 7221 : 1324. doi:10. 1136bmj. 319.

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In a study of healthy male volunteers, co-administration of sildenafil at steady state (80 mg t. ) with endothelin receptor antagonist bosentan (a moderate inducer of CYP3A4, CYP2C9 and possibly of CYP2C19) at steady state (125 mg b.

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