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Consistent with its known effects on the nitric oxidecGMP pathway, VIAGRA was shown to potentiate the hypotensive effects of nitrates [see DOSAGE AND ADMINISTRATIONCONTRAINDICATIONSCLINICAL PHARMACOLOGY ]. Alpha-blockers. Use caution when co-administering alpha-blockers with VIAGRA because of potential additive blood pressure-lowering effects. When VIAGRA is co-administered with an alpha-blocker, patients should be stable on alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated at the lowest dose [see DOSAGE AND ADMINISTRATIONWARNINGS AND PRECAUTIONSCLINICAL PHARMACOLOGY exit certification pfizer viagra. Amlodipine. When VIAGRA 100 mg was co-administered with amlodipine (5 mg or 10 mg) to hypertensive patients, the mean additional reduction on supine blood pressure was 8 mmHg qualifica istat operaio generico do viagra and 7 mmHg diastolic [see WARNINGS AND PRECAUTIONSCLINICAL PHARMACOLOGY ].

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