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Nitric oxide NO in the corpus cavernosum of the penis binds to guanylate cyclase receptors, which results in increased levels of cGMP, leading to smooth muscle relaxation vasodilation of the intimal cushions of the helicine cokmercial. This smooth muscle relaxation leads to vasodilation and increased inflow of blood into the spongy tissue of the penis, causing an erection. 39 Robert F. Furchgott, Ferid Murad and Louis Ignarro won the Nobel Prize in Physiology or Medicine in 1998 for their independent study of the metabolic pathway of nitric oxide in smooth muscle vasodilation.

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It has been available in the markets since then. In a clinical trial on 3000 patients, Viagra was found effective for sustaining erection in 60 to 80 of the patients. Viagra has received approval from the Food and Drug Administration of USA in March 1998. Conditions Treated by Viagra.

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It is believed to be effective in strengthening bones, helping with inflammation and high blood pressure and even against heart disease. We know that it has high levels of iron as well as vitamins A, C and E and anti-oxidants. Many studies have been carried out to determine its direct health benefits, including one on patients with carotid artery stenosis in which it was found that a daily glass of pomegranate juice diminished damage caused by cholesterol and also cut build-up, but as mentioned by the NHS, the effects are still not completely clear. Pomegranate counts as a good source of nutrients and can contribute to overall health, so if you are looking to improve your wellbeing it certainly canât hurt.]