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Product Description

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Mechanism Of Action. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum.

Detailed information

Alpha-blockers. Use caution when co-administering alpha-blockers with VIAGRA because of potential additive blood pressure-lowering effects. When VIAGRA is co-administered with an alpha-blocker, patients should be stable on alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated at the lowest dose [see DOSAGE AND ADMINISTRATIONWARNINGS AND PRECAUTIONSCLINICAL PHARMACOLOGY ]. Amlodipine.

Diarrhea Nasal congestion Facial flushing Vomiting or nausea Cold and flu signs or symptoms irritated in addition to rashes about skin color. Warnings of Generic Viagra(Sildenafil Citrate) without Prescription. Youngsters under the age of 18 years should not consume this medicine. Remember to step using the tablet once you experience any side effects and also consult doctor immediately. Check the results of the medicine regularly and have a daily check up with your family doctor. Always keep a positive thinking so enhance your erectile function smoothly.

Use Viagra Soft Safely. Viagra Soft can be taken only once a day half an hour before planned sexual intercourse. The duration of drug activity is 5 hours. A pill dissolves under a tongue immediately.]